Calsyntenin
Web开馆时间:周一至周日7:00-22:30 周五 7:00-12:00; 我的图书馆 WebJan 25, 2024 · Calsyntenin-3 (Clstn3) is a postsynaptic adhesion molecule that induces presynaptic differentiation via presynaptic neurexins (Nrxns), but whether Nrxns directly bind to Clstn3 has been a matter of debate. Here, we show that β-Nrxns directly interact via their LNS domain with Clstn3 and Clstn3 cadherin domains. Expression of splice site 4 (SS4) …
Calsyntenin
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Web↑ 1.0 1.1 1.2 Araki Y, Tomita S, Yamaguchi H, Miyagi N, Sumioka A, Kirino Y, Suzuki T (December 2003). "Novel cadherin-related membrane proteins, Alcadeins, enhance … WebCalsyntenin-1 is a neuronally enriched type-1 membrane-spanning protein that binds directly to KLCs via its intracellular C-terminal domain (13–16). As such, calsyntenin-1 acts as a ligand to mediate transport of a subset of vesicles through axons on kinesin-1 motors. A proportion of APP and calsyntenin-1 co-localize in cells and tissues, and ...
WebMar 29, 2024 · Vagnoni A, et al. Calsyntenin-1 mediates axonal transport of the amyloid precursor protein and regulates Aβ production. Hum. Mol. Genet. 2012;21:2845–2854. doi: 10.1093/hmg/dds109. Gotoh, N. et al. APP amyloidogenic processing is enhanced in the brains of Alcadein α-deficient mice. Under submission. Yagi T, et al. WebApr 14, 2024 · Deletion of Calsyntenin-3, an atypical cadherin, suppresses inhibitory synapses but increases excitatory parallel-fiber synapses in cerebellum Cadherins …
WebDec 5, 2024 · Calsyntenin 1 Gene CLSTN1 Status UniProtKB unreviewed (TrEMBL) Organism Homo sapiens (Human) Amino acids 373 Protein existence Evidence at protein level Annotation score 1/5 Entry Feature viewer Publications External links History BLAST Download Add Add a publication Entry feedback Function GO annotations Expand table WebJan 1, 2001 · We termed this protein calsyntenin-1, because it binds synaptic Ca 2+ with its cytoplasmic domain. By binding Ca 2+ , calsyntenin-1 may modulate Ca 2+ -mediated …
WebJun 25, 2014 · Calsyntenin-1 is a transmembrane cargo-docking protein important for kinesin-1-mediated fast transport of membrane-bound organelles that exhibits peak expression levels at postnatal day 7. However, its neuronal function during postnatal development remains unknown.
WebFeb 3, 2024 · Author Correction: Innervation of thermogenic adipose tissue via a calsyntenin 3β–S100b axis. Xing Zeng 1,2, Mengchen Ye 3, Jon M. Resch 4, Mark P. Jedrychowski 1,2, Bo Hu 1,2, Bradford B ... pilote joa 70qWebMay 31, 2024 · Thus, by promoting formation of an excitatory type of synapses and decreasing formation of an inhibitory type of synapses in the same neuron, calsyntenin … gummie pain pillsWeb人可溶性肌球蛋白重链1(sMHC-1)ELISA检测试剂盒企业。是国内生物试剂研发与生产,销售合为一体的创新型企业,产品... gummies marijuana in minnesotaWeb胎牛血清(杂交瘤细胞专用) sp2/0 小鼠骨髓瘤细胞. 佐剂乳化器 gummi fußmatten auto stinkenWebMar 12, 2024 · Calsyntenins (CLSTNs) are important synaptic molecules whose molecular functions are not fully understood. Although mutations in calsyntenin ( CLSTN) genes have been associated with psychiatric disorders in humans, their function is still unclear. gummies keto toneWebJul 14, 2015 · Calsyntenin-2, also known as alcadein-γ, is a neuronal cell surface synaptic protein with an evolutionarily conserved role in learning and memory. In humans, … gummies vitamins halalWebApr 28, 2024 · Retinal artery occlusion (RAO), retinal vein occlusion (RVO), diabetic retinopathy (DR) and age-related macular degeneration (AMD) are frequent ocular diseases with potentially sight-threatening outcomes. In the present review we discuss major findings of proteomic studies of RAO, RVO, DR and AMD, including an overview of ocular … pilote joa 70t 2022